Abstract Search

ea0081rc12.7 | Rapid Communications 12: Reproductive and Developmental Endocrinology | ECE2022

Pubertal induction in girls with hypogonadism: insight into estrogen replacement therapy outcomes and optimization of progesterone introduction

Rodari Giulia , Federici Silvia , Cattoni Alessandro , Todisco Tommaso , Ubertini Graziamaria , Giacchetti Federico , Profka Eriselda , Dall'Antonia Alberta , Cangiano Biagio , Arosio Maura , Bonomi Marco , Cappa Marco , Giavoli Claudia

Background: Pubertal induction in girls with hypogonadism through estrogen replacement therapy (ERT) aims at mimicking physiological puberty. To date, the best induction regimen is still to be established.Aims: By setting up a multicentre clinical registry, we analysed longitudinal data on pubertal induction in girls with hypogonadotropic hypogonadism or premature ovarian insufficiency (congenital, acquired, isolated or associated with multiple pituitary...

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ea0073aep857 | Late Breaking | ECE2021

SHBG as a Q1 marker of NAFLD and metabolic impairments in women referred for oligomenorrhea and/or hirsutism and in women with sexual dysfunction

Di Stasi Vincenza , Maseroli Elisa , Rastrelli Giulia , Scavello Irene , Cipriani Sarah , Todisco Tommaso , Marchiani Sara , Sorbi Flavia , Fambrini Massimiliano , Petraglia Felice , Maggi Mario , Vignozzi Linda

PCOS (Polycystic Ovary Syndrome) is one of the most common endocrine disorders and NAFLD (Nonalcoholic Fatty Liver Disease) is one of its most dangerous metabolic consequences. The diagnosis of NAFLD is not a practical task and the condition is at risk of being overlooked. The use of simpler but still reliable surrogate markers is necessary to identify women with a high likelihood of NAFLD. The aim of this study was to evaluate the clinical correlates of NAFLD Liver Fat Score ...

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ea0073aep803 | Late Breaking | ECE2021

Physical activity and female sexual dysfunction: too much of a good thing?

Maseroli Elisa , Rastrelli Giulia , Di Stasi Vincenza , Cipriani Sarah , Scavello Irene , Todisco Tommaso , Gironi Veronica , Castellini Giovanni , Ricca Valdo , Sorbi Flavia , Fambrini Massimiliano , Petraglia Felice , Maggi Mario , Vignozzi Linda

BackgroundResearch on the relationship between physical activity (PA) and female sexual dysfunction (FSD) is lacking.AimTo investigate the clinical, psychological, and sexual correlates of PA in women with FSD.MethodsA non-selected series of n = 322 pre- and post-menopausal patients consulting for FSD was retrospectively studied. Regular involvement in PA...

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ea0073aep835 | Late Breaking | ECE2021

Preliminary evidence of the role of circulating testosterone levels in a cohort of women with SARS-CoV-2 infection

Rastrelli Giulia , Di Stasi Vincenza , Inglese Francesco , Beccaria Massimiliano , Garuti Martina , Di Costanzo Domenica , Spreafico Fabio , Francesca Greco Graziana , Pecoriello Antonietta , Todisco Tommaso , Cipriani Sarah , Maseroli Elisa , Scavello Irene , Glingani Claudia , Franchini Massimo , Maggi Mario , De Donno Giuseppe , Vignozzi Linda

PurposeObjective of this study was to assess the association between testosterone (T) levels and biochemical markers in a cohort of female patients admitted for SARS-CoV-2 infection in a respiratory intensive care unit (RICU).MethodsA consecutive series of 17 women affected by SARSCoV-2 pneumonia and recovered in the RICU of the Hospital of Mantua (Italy) were analyzed. Biochemical inflammatory markers as wel...

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ea0073aep861 | Late Breaking | ECE2021

Insight on the intracrinology of menopause: androgen production within the human vagina

Cipriani Sarah , Cellai Ilaria , Di Stasi Vincenza , Comeglio Paolo , Maseroli Elisa , Todisco Tommaso , Corno Chiara , Filippi Sandra , Sorbi Flavia , Fambrini Massimiliano , Petraglia Felice , Scavello Irene , Rastrelli Giulia , Acciai Gabriele , Villanelli Fabio , Danza Giovanna , Sarchielli Erica , Guarnieri Giulia , Morelli Annamaria , Maggi Mario , Vignozzi Linda

In this study, we investigated steroidogenic gene mRNA expression in human vagina and verified the ability of human vagina smooth muscle cells (hvSMCs) to synthesize androgens from upstream precursor dehydroepiandrosterone (DHEA). As a readout for androgen receptor (AR) activation, we evaluated the mRNA expression of various androgen-dependent markers. hvSMCs were isolated from vagina tissues of women undergoing surgery for benign gynecological diseases. In these cells, we eva...

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Endocrine Abstracts

Pubertal induction in girls with hypogonadism: insight into estrogen replacement therapy outcomes and optimization of progesterone introduction

SHBG as a Q1 marker of NAFLD and metabolic impairments in women referred for oligomenorrhea and/or hirsutism and in women with sexual dysfunction

Physical activity and female sexual dysfunction: too much of a good thing?

Preliminary evidence of the role of circulating testosterone levels in a cohort of women with SARS-CoV-2 infection

Insight on the intracrinology of menopause: androgen production within the human vagina

BiosciAbstracts